GREEN TEA EXTRACT LOADED INTO SOLID LIPID NANOPARTICLES

被引:0
作者
Manea, Ana-Maria [1 ]
Andronescu, Corina [2 ]
Meghea, Aurelia [1 ]
机构
[1] Univ Politehn Bucuresti, Fac Appl Chem & Mat Sci, Bucharest, Romania
[2] Univ Politehn Bucuresti, Adv Polymer Mat Grp, Bucharest, Romania
来源
UNIVERSITY POLITEHNICA OF BUCHAREST SCIENTIFIC BULLETIN SERIES B-CHEMISTRY AND MATERIALS SCIENCE | 2014年 / 76卷 / 02期
关键词
solid lipid nanoparticles; green tea extract; high shear homogenization;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The aim of this study was to synthesize by high shear homogenization method and to characterize new solid lipid nanoparticles loaded with green tea extract, nanoparticles which show high antioxidant activity. In this respect, cetyl palmitate and glyceryl stearate were used as solid lipids in combination with two nonionic surfactants, Tween20 and Tween80 and an ionic surfactant as lecithin. The obtained solid lipid nanoparticles have been firstly characterized by particle diameter and physical stability using dynamic light scattering method. The particle morphology was examined by transmission electron microscopy. The antioxidant and antimicrobial properties of new developed nano-materials have been also evaluated.
引用
收藏
页码:125 / 136
页数:12
相关论文
共 28 条
  • [1] Effects of mechanical processing on phase composition
    Brittain, HG
    [J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 2002, 91 (07) : 1573 - 1580
  • [2] Solid lipid nanoparticles (SLN) as ocular delivery system for tobramycin
    Cavalli, R
    Gasco, MR
    Chetoni, P
    Burgalassi, S
    Saettone, MF
    [J]. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2002, 238 (1-2) : 241 - 245
  • [3] Podophyllotoxin-loaded solid lipid nanoparticles for epidermal targeting
    Chen, HB
    Chang, XL
    Du, DR
    Liu, W
    Liu, J
    Weng, T
    Yang, YJ
    Xu, HB
    Yang, XL
    [J]. JOURNAL OF CONTROLLED RELEASE, 2006, 110 (02) : 296 - 306
  • [4] Lipophilic drug derivatives in liposomes
    Gulati, M
    Grover, M
    Singh, S
    Singh, M
    [J]. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1998, 165 (02) : 129 - 168
  • [5] Effect of surfactant surface coverage on formation of solid lipid nanoparticles (SLN)
    Helgason, T.
    Awad, T. S.
    Kristbergsson, K.
    McClements, D. J.
    Weiss, J.
    [J]. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2009, 334 (01) : 75 - 81
  • [6] A novel phase inversion-based process for the preparation of lipid nanocarriers
    Heurtault, B
    Saulnier, P
    Pech, B
    Proust, JE
    Benoit, JP
    [J]. PHARMACEUTICAL RESEARCH, 2002, 19 (06) : 875 - 880
  • [7] Preparation of solid lipid nanoparticles with clobetasol propionate by a novel solvent diffusion method in aqueous system and physicochemical characterization
    Hu, FQ
    Yuan, H
    Zhang, HH
    Fang, M
    [J]. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2002, 239 (1-2) : 121 - 128
  • [8] Humberstone AJ, 1997, ADV DRUG DELIVER REV, V25, P103, DOI 10.1016/S0169-409X(96)00494-2
  • [9] Hunter R. J., 1986, FDN COLLOIDAL SCI, V1
  • [10] Antibacterial and antioxidant activities of grape (Vitis vinifera) seed extracts
    Jayaprakasha, GK
    Selvi, T
    Sakariah, KK
    [J]. FOOD RESEARCH INTERNATIONAL, 2003, 36 (02) : 117 - 122