The aim of this study was to investigate the effect of impulse noise on birth weight of pregnant rats. A total of 24 female rat divided to impulse noise (10 rats) and control groups (14 rats) and are mated with two male rat weighed 300 +/- 25 gr. The rats in impulse noise group were exposed 300 Hz-8 KHz, 120 dB disco music 10x20 min/day. From each group, six rats that each one of them is delivered seven infant were included statistical analysis. The median weight of mother rats were similar between impulse noise and control groups ((271 gr [226-282] vs. 274 gr [240-290 respectively p=0,423). The median birtweigth of the rats in the impulse noise group was significantly lower than that of control group ((4,4[3-5,4]) vs. 6[3,3-6,5] respectively, p<0,001). The effect of impulse noise on birtweigt was maintained when rats were stratified by sex. This study shows that high level of impulse noise lasting a significant length of time can cause low birthweight in pregnant rats.
机构:
UNIV WISCONSIN,SCH MED,EAU CLAIRE FAMILY PRACTICE RESIDENCY PROGRAM,EAU CLAIRE,WI 54701UNIV WISCONSIN,SCH MED,EAU CLAIRE FAMILY PRACTICE RESIDENCY PROGRAM,EAU CLAIRE,WI 54701
MAINOUS, AG
HUESTON, WJ
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UNIV WISCONSIN,SCH MED,EAU CLAIRE FAMILY PRACTICE RESIDENCY PROGRAM,EAU CLAIRE,WI 54701UNIV WISCONSIN,SCH MED,EAU CLAIRE FAMILY PRACTICE RESIDENCY PROGRAM,EAU CLAIRE,WI 54701
机构:
Univ Paris Cite, HERA team, Inrae, Inserm,U1153,CRESS, Paris, France
Univ Paris Cite, Fac Pharm Paris, Paris, France
Fac Pharm Paris, 4 Ave Observ, F-75270 Paris 06, FranceUniv Paris Cite, HERA team, Inrae, Inserm,U1153,CRESS, Paris, France
Ranciere, Fanny
Wafo, Octave
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Univ Paris Cite, HERA team, Inrae, Inserm,U1153,CRESS, Paris, FranceUniv Paris Cite, HERA team, Inrae, Inserm,U1153,CRESS, Paris, France
Wafo, Octave
Perrot, Xavier
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CNRS, Ecole Normale Super, Lab Meteorol Dynam, Paris, FranceUniv Paris Cite, HERA team, Inrae, Inserm,U1153,CRESS, Paris, France
Perrot, Xavier
Momas, Isabelle
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Univ Paris Cite, HERA team, Inrae, Inserm,U1153,CRESS, Paris, France
Univ Paris Cite, Fac Pharm Paris, Paris, France
Direct Act Sociale Enfance & Sante, Cellule Cohorte, Mairie Paris, Paris, FranceUniv Paris Cite, HERA team, Inrae, Inserm,U1153,CRESS, Paris, France