VIMENTIN EXPRESSION BY REED-STERNBERG CELLS IN HODGKINS-DISEASE

被引：6
作者：
ANGEL, CA
CULLEN, RA
PRINGLE, JH
LAUDER, I
机构：
[1] UNIV LEICESTER,LEICESTER ROYAL INFIRM,DEPT PATHOL,LEICESTER LE1 7RH,ENGLAND
[2] LEICESTER ROYAL INFIRM,DEPT HISTOPATHOL,LEICESTER LE2 7LX,ENGLAND
来源：
VIRCHOWS ARCHIV A-PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY | 1992年 / 421卷 / 01期
关键词：
VIMENTIN; REED-STERNBERG CELLS; HODGKINS DISEASE; IMMUNOHISTOLOGY;
D O I：
10.1007/BF01607132
中图分类号：
R602 [外科病理学、解剖学]; R32 [人体形态学];
学科分类号：
100101 ;
摘要：
The expression of vimentin in Reed-Sternberg cells in 61 samples of Hodgkin's disease (HD) was examined using an avidin-biotin-peroxidase complex technique. Forty biopsies (66%) expressed vimentin, and expression was seen in all subtypes of HD. No immunophenotypic differences between vimentin-positive and vimentin-negative cases were noted. The significance of such expression is unclear, but may be related to the alterations in growth and differentiation that are typical of neoplastic cells.
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页码：9 / 11
页数：3
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