SENSORY NEUROPATHY ASSOCIATED WITH MONOCLONAL IMMUNOGLOBULIN-M TO GD1B GANGLIOSIDE

被引：68

作者：

DAUNE, GC

FARRER, RG

DALAKAS, MC

QUARLES, RH

机构：

[1] NINCDS, MOLEC & CELLULAR NEUROBIOL LAB, MYELIN & BRAIN DEV SECT, PK BLDG, BETHESDA, MD 20892 USA

[2] NINCDS, MED NEUROL BRANCH, NEUROMUSCULAR DIS SECT, BETHESDA, MD 20892 USA

来源：

ANNALS OF NEUROLOGY | 1992年 / 31卷 / 06期

关键词：

D O I：

10.1002/ana.410310621

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A 67-year-old woman with a sensory polyneuropathy was shown to have a serum monoclonal immunoglobulin M-lambda antibody with a titer of 1: 10,000 toward GD1b ganglioside. The immunoglobulin M also reacted with some other gangliosides containing disialosyl groups such as GD2, GD3, and GQ1b, but it did not react with GM 1, LM1, or GD1a. The principal reactive ganglioside in human cauda equina was GD1b.

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页码：683 / 685

页数：3

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