OXIDATION OF ALPHA-AMINO ESTERS - ONE-STEP SYNTHESIS OF SULFENIMINES

被引：18

作者：

GORDON, EM

PLUSCEC, J

机构：

[1] Squibb Institute for Medical Research, New Jersey, Princeton

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1979年 / 44卷 / 08期

关键词：

D O I：

10.1021/jo01322a006

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

α-Amino esters (1) were oxidized to their corresponding sulfenimine derivatives (2) by mild treatment with ptoluenesulfenyl chloride in the presence of acid scavengers. Such amino acid derived sulfenimines are converted to α-keto esters by treatment with triphenylphosphine and silica gel. Oxidation of sulfenimines is discussed, including an example which gives rise to a dehydroamino acid residue. © 1979, American Chemical Society. All rights reserved.

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页码：1218 / 1221

页数：4

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