SCANNING ELECTRON-MICROSCOPIC STUDY OF ENDOTHELIAL-CELLS OF CEREBRAL-ARTERIES FROM SPONTANEOUSLY HYPERTENSIVE RATS

被引：67
作者：
HAZAMA, F [1 ]
OZAKI, T [1 ]
AMANO, S [1 ]
机构：
[1] KYOTO UNIV,SCH MED,DEPT NEUROL,KYOTO 606,JAPAN
来源：
STROKE | 1979年 / 10卷 / 03期
关键词：
D O I：
10.1161/01.STR.10.3.245
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Endothelial cells of the cerebral arterial system in spontaneously hypertensive rats were investigated by scanning electronmicroscopy and found to show progressive changes such as increased microvilli, numerous plasmalemmal pits, enlargement of the cells and well-developed marginal folds. Regressive changes, such as balloon-like protrusions and crater-like cave-ins, were also observed. Platelet adhesion to the injured endothelial surface of cerebral arteries was frequent. The significance of these changes in the development of hypertensive cerebrovascular lesions is discussed. © 1979 American Heart Association, Inc.
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页码：245 / 252
页数：8
相关论文
共 20 条
  • [1] ENDOTHELIAL MICROVILLI IN VESSELS OF RAT GASSERIAN GANGLION AND TESTIS
    GABBIANI, G
    MAJNO, G
    [J]. ZEITSCHRIFT FUR ZELLFORSCHUNG UND MIKROSKOPISCHE ANATOMIE, 1969, 97 (01): : 111 - +
  • [2] AUTORADIOGRAPHIC INVESTIGATION OF CELL-PROLIFERATION IN BRAIN OF SPONTANEOUSLY HYPERTENSIVE RATS
    HAZAMA, F
    HAEBARA, H
    AMANO, S
    OZAKI, T
    [J]. ACTA NEUROPATHOLOGICA, 1977, 37 (03) : 231 - 236
  • [3] VASCULAR-LESIONS IN VARIOUS SUBSTRAINS OF SPONTANEOUSLY HYPERTENSIVE RATS AND EFFECTS OF CHRONIC SALT INGESTION
    HAZAMA, F
    OOSHIMA, A
    TANAKA, T
    TOMIMOTO, K
    OKAMOTO, K
    [J]. JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION, 1975, 39 (01): : 7 - 22
  • [4] HAZAMA F, 1975, ACTA PATHOL JAPON, V25, P565
  • [5] HAZAMA F, 1975, CEREBRAL VESSEL WALL, P245
  • [6] HAZAMA F, 1975, 6TH INT C NEUR AMST, P517
  • [7] SCANNING ELECTRON MICROSCOPIC OBSERVATIONS ON LUMINAL SURFACE OF RABBIT COMMON CAROTID ARTERY SUBJECTED TO ISCHEMIA BY ARTERIAL OCCLUSION
    KAWAMURA, J
    GERTZ, SD
    SUNAGA, T
    RENNELS, ML
    NELSON, E
    [J]. STROKE, 1974, 5 (06) : 765 - 774
  • [8] NELSON E, 1975, CEREBRAL VESSEL WALL, P33
  • [9] OKAMOTO KOZO, 1963, JAPAN CIRCULATION JOUR, V27, P282
  • [10] PLATELET-DEPENDENT SERUM FACTOR THAT STIMULATES PROLIFERATION OF ARTERIAL SMOOTH-MUSCLE CELLS INVITRO
    ROSS, R
    GLOMSET, J
    KARIYA, B
    HARKER, L
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1974, 71 (04) : 1207 - 1210
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