Novel Synthesis of Fused Pyrazolopyrimidines and C-Nucleosides of Thienopyrimidone with Expected Antimicrobial Activity

被引：0
|
作者：
Hussein, H. A. R. [1 ]
Abu-Zied, Kh. M. [1 ]
Abu-Hashem, A. A. [1 ]
机构：
[1] Natl Res Ctr, Dept Photochem, Heterocycl Unit, Cairo, Egypt
来源：
EGYPTIAN JOURNAL OF CHEMISTRY | 2010年 / 53卷 / 04期
关键词：
Pyrazolopyrimidine; C-Nucleosides; NMR spectra; Mass spectra; Antibacterial and Antifungal Activities;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
STARTING from thienopyrimidine hydrazine derivatives (1a, d) and (2b, c) a series of pyrazolopyrimidine derivatives has been synthesized. Also, some acyclic and cyclic C-nucleosides of thienopyrimidone (7-10) were prepared by treating compound 1a with aldoses. The prepared products showed antimicrobial activity. Structures of the new compounds were elucidated on the basis of their elemental analyses and spectral data.
引用
收藏
页码：527 / 540
页数：14
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