COMPLEX GENETIC EFFECT OF B10.D2 (M504) (H-2DM1) MUTATION

Serological and capping experiments show that the strain B10.D2 (M504) carrying the mutant haplotype H-2d m1 has two molecules in the products of the D region: H-2Ddm1 and H-2Ldm1 which are detectable by anti-H-2.4 and by anti-H-2.28 sera, respectively. Both these molecules differ serologically from the H-2Dd and H-2Ld molecules of the original (nonmutant) strain B10.D2. A third molecule, different from H-2D and H-2L, was detected in H-2d, H-2d m2 but not in H-2dm1 products. © 1979 Springer-Verlag New York Inc.