USE OF BIOLOGICAL STIMULUS IN DETERMINING PARAMETERS OF DRUG ACTION, AND ITS RELATIONSHIP TO DRUG EFFECT - CONTRIBUTION TO THEORY OF DRUG ACTION

被引：18

作者：

GERO, A

TALLARIDA, RJ

机构：

[1] HAHNEMANN MED COLL & HOSP,DEPT PHARMACOL,PHILADELPHIA,PA 19102

[2] TEMPLE UNIV,SCH MED,DEPT PHARMACOL,PHILADELPHIA,PA 19140

来源：

JOURNAL OF THEORETICAL BIOLOGY | 1977年 / 69卷 / 02期

关键词：

D O I：

10.1016/0022-5193(77)90135-7

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

收藏

页码：265 / 274

页数：10

相关论文

共 14 条

[1] ARIENS EJ, 1956, ARZNEIMITTEL-FORSCH, V6, P611
[2] ARIENS EJ, 1956, ARZNEIMITTEL-FORSCH, V6, P282
[3] AFFINITY AND EFFICACY OF ONIUM SALTS ON FROG RECTUS ABDOMINIS
BARLOW, RB
SCOTT, NC
STEPHENSON, RP
[J]. BRITISH JOURNAL OF PHARMACOLOGY AND CHEMOTHERAPY, 1967, 31 (01): : 188 - +
[4] COMPARISON OF DISSOCIATION CONSTANTS AND OF RELATIVE EFFICACIES OF SELECTED AGONISTS ACTING ON PARASYMPATHETIC RECEPTORS
FURCHGOTT, RF
BURSZTYN, P
[J]. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1967, 144 (A2) : 882 - +
[5] ON APPLICATION OF A PLAUSIBLE MODEL OF ALLOSTERIC PROTEINS TO RECEPTOR FOR ACETYLCHOLINE
KARLIN, A
[J]. JOURNAL OF THEORETICAL BIOLOGY, 1967, 16 (02) : 306 - &
[6] A STUDY OF THE DESENSITIZATION PRODUCED BY ACETYLCHOLINE AT THE MOTOR END-PLATE
KATZ, B
THESLEFF, S
[J]. JOURNAL OF PHYSIOLOGY-LONDON, 1957, 138 (01): : 63 - 80
[7] MARANO M, 1976, J PHARMACOL EXP THER, V198, P518
[8] ON NATURE OF ALLOSTERIC TRANSITIONS - A PLAUSIBLE MODEL
MONOD, J
WYMAN, J
CHANGEUX, JP
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1965, 12 (01) : 88 - &
[9] RECEPTOR OCCUPANCY AND TISSUE RESPONSE
NICKERSON, M
[J]. NATURE, 1956, 178 (4535) : 697 - 698
[10] PARKER RB, 1972, J PHARMACOL EXP THER, V180, P62