PERFLUOROALKYLATIONS AND PERFLUOROOXAALKYLATIONS .1. BROMOAROMATICS AS SUBSTRATES IN COPPER-MEDIATED CROSS-COUPLING

被引：11

作者：

CHEN, GJ ^{[1
]}

CHEN, LS ^{[1
]}

EAPEN, KC ^{[1
]}

机构：

[1] UNIV DAYTON,RES INST,DAYTON,OH 45469

来源：

JOURNAL OF FLUORINE CHEMISTRY | 1993年 / 63卷 / 1-2期

关键词：

D O I：

10.1016/S0022-1139(00)80402-9

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Tribromobenzenes, bromobiphenyl ethers and a bromoterphenyl ether have been used as substrates in copper-mediated cross-coupling reactions with perfluoroalkyl and per fluorooxaalkyl iodides. Excellent yields were obtained from perfluoroalkyl iodides as well as the ether iodides in which the ether oxygen was situated at position 5 or higher. However, ether iodides where the ether oxygen was at the 3-position gave only traces of the cross-coupled product, if any. This difference in reactivity is based on the relative position of the ether linkage to the reaction site and was more pronounced in reactions with aryl bromides than in reactions with aryl iodides.

引用

页码：113 / 123

页数：11

共 12 条

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[2]

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