RECENT ADVANCES IN B-CELL ACUTE LYMPHOBLASTIC-LEUKEMIA (BURKITT LEUKEMIA) THERAPY IN CHILDHOOD

被引：0
作者：
BARUCHEL, A
SCHAISON, G
机构：
来源：
NOUVELLE REVUE FRANCAISE D HEMATOLOGIE | 1993年 / 35卷 / 01期
关键词：
B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA; CHILDHOOD;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Acute lymphoblastic leukemia with Burkitt type cells has been described in 1975. Until the mid-1980, with conventional treatments, the prognosis was very poor with very few long-term survivors. Failures were mainly due to central nervous system involvement at diagnosis or relapse. After that period a dramatic improvement has been observed with intensified treatments based on Burkitt's lymphoma therapy regimens. High-dose cyclophosphamide, high-dose methotrexate, high-dose ara-C in compact protocols completed in 6-7 months have been proven useful. 75 % of the patients can be cured.
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页码：106 / 108
页数：3
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