STRUCTURAL COMPARISON OF UREASE AND A GROEL ANALOG FROM HELICOBACTER-PYLORI

被引：29

作者：

AUSTIN, JW

DOIG, P

STEWART, M

TRUST, TJ

机构：

[1] UNIV VICTORIA,DEPT BIOCHEM & MICROBIOL,VICTORIA V8W 3P6,BC,CANADA

[2] UNIV VICTORIA,CANADIAN BACTERIAL DIS NETWORK,VICTORIA V8W 3P6,BC,CANADA

[3] MRC,MOLEC BIOL LAB,CAMBRIDGE CB2 2QH,ENGLAND

来源：

JOURNAL OF BACTERIOLOGY | 1992年 / 174卷 / 22期

关键词：

D O I：

10.1128/jb.174.22.7470-7473.1992

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Electron microscopy of purified protein preparations indicated that Helicobacter pylori urease consisted of circular particles that are 13 nm in diameter, some of which showed indications of threefold rotational symmetry. A GroEL analog of H. pylori (Hp60K) appeared as a disc-shaped molecule with a diameter similar to that of urease but possessed sevenfold rotational symmetry. In a side-view projection, Hp60K appeared as two or four discs stacked side by side.

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页码：7470 / 7473

页数：4

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