Ventricular arrhythmias in patients with Takotsubo syndrome

被引:43
作者
Moeller, Christian [1 ,2 ]
Eitel, Charlotte [1 ,2 ]
Thiele, Holger [1 ,2 ]
Eitel, Ingo [1 ,2 ]
Stiermaier, Thomas [1 ,2 ]
机构
[1] Univ Heart Ctr Lubeck, Med Clin 2, Dept Cardiol Angiol & Intens Care Med, Lubeck, Germany
[2] German Ctr Cardiovasc Res DZHK, Partner Site Hamburg Kiel Lubeck, Lubeck, Germany
关键词
implantable cardioverter-defibrillator; Takotsubo syndrome; ventricular arrhythmias;
D O I
10.1002/joa3.12029
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Takotsubo syndrome (TTS) is a unique nonischemic cardiac disease characterized by acute myocardial dysfunction of the left and/or right ventricle. Patients are predominantly postmenopausal women and usually present with symptoms indistinguishable from acute coronary syndrome. Although the exact pathomechanisms of TTS remain elusive, increasing evidence suggests that sympathetic overdrive and catecholamine excess might play a central role. Despite the complete recovery of ventricular dysfunction within several days to weeks, patients with TTS exhibit considerable short- and long-term mortality rates and ventricular arrhythmias have been identified as key contributor to morbidity and mortality. This article summarizes the prevalence, underlying mechanisms, therapeutic strategies, and prognostic implications of ventricular arrhythmias in TTS. Furthermore, the need for implantable cardioverter-defibrillators is discussed in view of the transient character of the disease.
引用
收藏
页码:369 / 375
页数:7
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