Neuropsychiatric and neuropsychological manifestations of Systemic Lupus Erythematosus

被引:1
作者
Rios-Florez, Jorge Alexander [1 ,2 ]
Escudero-Corrales, Carolina [3 ,4 ,5 ]
Rocio Lopez-Gutierrez, Claudia [6 ,7 ,8 ]
机构
[1] Univ Fed Rio Grande do Norte, Natal, RN, Brazil
[2] Grp Estudio Invest Neurociencias Hippocampus, Natal, RN, Brazil
[3] Univ Pontificia Bolivariana, Medellin, Colombia
[4] Grp Estudio Invest Neurociencias HIPPOCAMPUS, Linea Invest Trastornos Neurol Adultez, Medellin, Colombia
[5] Grp Estudio Invest Neurociencias HIPPOCAMPUS, Linea Estudio Neurociencia, Medellin, Colombia
[6] Univ Catolica Luis Amigo, Medellin, Colombia
[7] Grp Estudio Invest Neurociencias Hippocampus, Linea Invest Sindromes Neurol Infancia, Medellin, Colombia
[8] Grp Estudio Invest Neurociencias Hippocampus, Linea Estudio Neurociencia Afect & Emoc, Medellin, Colombia
来源
REVISTA CUBANA DE REUMATOLOGIA | 2018年 / 20卷 / 01期
关键词
Anxiety; Autoimmune; Cognition; Depression; Systemic Lupus Erythematosus; SLE; Neuropsychology;
D O I
10.5281/zenodo.1174909
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The objective of this research was to determine the neuropsychological and neuropsychiatric sequelae associated with Systemic Lupus Erythematosus. A comparative-correlational analysis design was proposed, in a study of 68 individuals, a clinical group consisted of 34 patients diagnosed with Systemic Lupus Erythematosus and the control with 34 people in an even condition to each patient, in relation to age, gender and degree. The entire profile of neurocognitive functioning and emotional and behavioral psychiatric symptoms associated with depression and anxiety were analyzed, correlated to variables such as age, time of onset development of the symptoms of Systemic Lupus Erythematosus and the time of diagnosis after the onset of symptoms. The results suggest patterns of neuropsychiatric pathology characteristic of depression and anxiety disorders such as comorbidity and not as a sequel to Systemic Lupus Erythematosus. No difficulties in recognizing complex emotions. With short and long term verbal memory deficit for extensive contents, short and long term visual memory failures. They did not show commitment in processes of comprehension or verbal fluency. With alteration in executive functions, mainly monitoring and regulation of behavior. Failures in attentional processes in patients with depressive symptoms; Those who have anxiety have altered the speed of information processing. The Systemic Lupus Erythematosus as autoimmune pathology functionally affects not only the quality of life of the patient and their daily life at motor level, it also entails a neuropsychological deterioration profile that is associated to the moment of symptom manifestation and to the time that has elapsed until the diagnosis was established, from which the intensity and evolution of neurofunctional deterioration derive.
引用
收藏
页数:29
相关论文
共 73 条
[1]  
Aguilera Pickens G, 2013, REUMATOLOGIA CLIN, V9, P1, DOI [10.1016/j.reuma.2013.02.007, DOI 10.1016/J.REUMA.2013.02.007]
[2]  
[Anonymous], 2009, TEST COPIA FIGURA CO
[3]   Acute psychosis in systemic lupus erythematosus [J].
Appenzeller, Simone ;
Cendes, Fernando ;
Lavras Costallat, Lilian Tereza .
RHEUMATOLOGY INTERNATIONAL, 2008, 28 (03) :237-243
[4]   Cognitive Impairment and Employment Status in Systemic Lupus Erythematosus: A Prospective Longitudinal Study [J].
Appenzeller, Simone ;
Cendes, Fernando ;
Costallat, Lilian T. L. .
ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH, 2009, 61 (05) :680-687
[5]  
Ardila A., 2012, GUIA DIAGNOSTICO NEU
[6]  
Ardila A, 2007, EVALUACION NEUROPSIC
[7]  
Ardila A., 2012, REV NEUROPSICOLOGIA, V12, P1
[8]  
Ariza K, 2010, TER PSICOL, V28, P27
[9]   Is there a ''language of the eyes''? Evidence from normal adults, and adults with autism or Asperger Syndrome [J].
BaronCohen, S ;
Wheelwright, S ;
Jolliffe, T .
VISUAL COGNITION, 1997, 4 (03) :311-331
[10]  
Beck A., 2002, INVENTARIO ANSIEDAD