ALTERATION OF NA+ PERMEABILITY IN HUMAN ERYTHROCYTES AS STUDIED BY NA-23-NMR AND INHIBITION OF THE KIDNEY NA+,K+-ATPASE ACTIVITIES WITH SAPONINS - INTERACTION OF GLEDITSIA SAPONINS WITH HUMAN ERYTHROCYTE-MEMBRANES

被引：14
|
作者：
HARUNA, M
TANAKA, M
SUGIMOTO, T
KOJIMA, R
SUZUKI, Y
KONOSHIMA, T
KOZUKA, M
ITO, K
机构：
[1] MEIJO UNIV, FAC PHARM, DEPT PHARMACOL, NAGOYA, AICHI 468, JAPAN
[2] KYOTO PHARMACEUT UNIV, YAMASHIMA KU, KYOTO 607, JAPAN
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1995年 / 5卷 / 08期
关键词：
D O I：
10.1016/0960-894X(95)00121-9
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Interaction of Gleditsia saponin C 1, bis-monoterpenyl echinocystic acid 3,28-O-bisglycoside, with human erythrocyte membranes and artificial membranes was investigated by means of the hemolytic activities, alteration of Na+ permeability by Na-23-NMR spectroscopy and inhibition of Na+,K+-ATPase activities.
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收藏
页码：827 / 830
页数：4
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