P-GLYCOPROTEINS IN NEMATODES

被引：0
|
作者：
SANGSTER, NC
机构：
来源：
PARASITOLOGY TODAY | 1994年 / 10卷 / 08期
关键词：
D O I：
暂无
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
The P-glycoprotein (Pgp), a member of a group of integral membrane proteins that contain the ATP-binding cassette, is widely represented in the animal kingdom. A family of Pgp homologues has recently been described in nematodes. Pgps have been implicated in drug resistance in Plasmodium acid in other parasitic protozoa, so the interest of parasitologists now focuses on whether or not they are involved in anthelmintic resistance. Their role in normal cellular functions is also discussed in this article by Nick Sangster.
引用
收藏
页码：319 / 322
页数：4
相关论文
共 50 条
  • [1] THE BIOLOGY OF THE P-GLYCOPROTEINS
    LEVEILLEWEBSTER, CR
    ARIAS, IM
    JOURNAL OF MEMBRANE BIOLOGY, 1995, 143 (02): : 89 - 102
  • [2] Topology of P-glycoproteins
    Skach, WR
    ABC TRANSPORTERS: BIOCHEMICAL, CELLULAR, AND MOLECULAR ASPECTS, 1998, 292 : 265 - 278
  • [3] P-glycoproteins and multidrug resistance
    Bellamy, WT
    ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, 1996, 36 : 161 - 183
  • [4] P-glycoproteins are not released into bile
    Accatino, L
    Pizarro, M
    Solís, N
    Koenig, CS
    Vollrath, V
    Chianale, J
    JOURNAL OF HEPATOLOGY, 1998, 28 (04) : 741 - 741
  • [5] BIOCHEMISTRY OF HUMAN P-GLYCOPROTEINS, THE MULTIDRUG TRANSPORTER
    UEDA, K
    NIPPON NOGEIKAGAKU KAISHI-JOURNAL OF THE JAPAN SOCIETY FOR BIOSCIENCE BIOTECHNOLOGY AND AGROCHEMISTRY, 1992, 66 (11): : 1617 - 1624
  • [6] Genetic dissection of the function of mammalian P-glycoproteins
    Borst, P
    Schinkel, AH
    TRENDS IN GENETICS, 1997, 13 (06) : 217 - 222
  • [7] P-glycoproteins in anthelmintic safety, efficacy, and resistance
    Lespine, Anne
    Blancfuney, Clara
    Prichard, Roger
    Alberich, Melanie
    TRENDS IN PARASITOLOGY, 2024, 40 (10) : 896 - 913
  • [8] FUNCTIONAL EXPRESSION OF P-GLYCOPROTEINS IN SECRETORY VESICLES
    RUETZ, S
    GROS, P
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1994, 269 (16) : 12277 - 12284
  • [9] Chemical chaperones and folding defects in P-glycoproteins
    Clarke, D
    Loo, TW
    PROTEIN SCIENCE, 2004, 13 : 57 - 57
  • [10] Role of multidrug resistance P-glycoproteins in cholesterol biosynthesis
    Metherall, JE
    Li, HJ
    Waugh, K
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (05) : 2634 - 2640
12345