HETEROCYCLES WITH AN AZAALLYL SYSTEM .4. 5H-DIBENZ[C,E]AZEPINES WITH DONOR GROUPS AT THE 7-POSITION

被引：3

作者：

ROHRKASTEN, R ^{[1
]}

KREHER, RP ^{[1
]}

机构：

[1] UNIV DORTMUND,FACHBEREICH CHEM,LEHRSTUHL ORGAN CHEM 2,POSTFACH 50 05 00,W-4600 DORTMUND 50,GERMANY

来源：

CHEMISCHE BERICHTE | 1991年 / 124卷 / 09期

关键词：

5H-DIBENZ[C; E]AZEPINES; IMIDATES; ALKYL; HETEROCYCLIC;

D O I：

10.1002/cber.19911240934

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

5H-Dibenz[c,e]azepines substituted with a methoxy (1) or methylthio group (10) at the 7-position have been synthesized from 6,7-dihydro-5H-dibenz[c,e]azepin-5-one (5) by regioselective O- or S-alkylation with methyl trifluoromethansulfonate and subsequent NH-deprotonation. According to the spectroscopic properties the semicyclic 7-membered alkyl imidates exist exclusively in the benzenoid 5H structure.

引用

页码：2085 / 2090

页数：6

共 26 条

[1] ABSOLUTE CONFORMATION OF CHYMORTRYPSIN-BOUND SUBSTRATES . SPECIFIC RECOGNITION BY ENZYME OF BIPHENYL ASYMMETRY IN A CONSTRAINED SUBSTRATE [J].