ADENYLATE-CYCLASE ACTIVITY IN THE FAMILIES OF ALCOHOLICS IS CONTROLLED BY A SINGLE MAJOR GENE

被引：0

作者：

DEVOR, EJ ^{[1
]}

CLONINGER, CR ^{[1
]}

HOFFMAN, PL ^{[1
]}

TABAKOFF, B ^{[1
]}

机构：

[1] NIAAA,BETHESDA,MD 20892

来源：

ALCOHOL AND ALCOHOLISM | 1991年

关键词：

ADENYLATE CYCLASE; ALCOHOLISM; FAMILY STUDY; GENETICS; SEGREGATION ANALYSIS; MAJOR GENE;

D O I：

暂无

中图分类号：

R194 [卫生标准、卫生检查、医药管理];

学科分类号：

摘要：

The stimulated activity of platelet adenylate cyclase (AC) has been shown to be significantly lower among alcoholics compared with controls. In this report we demonstrate that stimulated platelet AC activity is under the control of a single major gene locus. Thus a sensitive biological indicator of alcoholism has been shown to be highly heritable.

引用

页码：157 / 160

页数：4

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