STUDIES ON CHEMOTAXIS .X. INHIBITION OF CHEMOTAXIS OF RABBIT NEUTROPHIL POLYMORPHONUCLEAR LEUCOCYTES

被引：22
作者：
KELLER, HU
SORKIN, E
机构：
[1] Institute for Medical Research, London, NW 7, Mill Hill
[2] Schweizerisches Forschungsinstitut, Medizinische Abteilung
来源：
INTERNATIONAL ARCHIVES OF ALLERGY AND APPLIED IMMUNOLOGY | 1968年 / 34卷 / 05期
关键词：
D O I：
10.1159/000230145
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
Inhibition of chemotaxis ofrabbit neutrophil polymorphonuclear leucocytes was studied in vitro. Cytotaxin formation in rabbit serum induced by antigen-antibody complexes was inhibited by 0.05 M N-CBZ-glycyl-L-phenylalanine, but not by 0.06 m ɛ-amino carpoic acid. N-CBZ- a-glutamyl-L-tyrosine failed to inactivate antigen-antibody treated serum. Polymorphs were found to be susceptible to repeated chemotactic stimulation, but incubation with washed immune complexes results in reduced responsiveness. © 1968 S. Karger AG, Basel.
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页码：513 / &
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