PHAGOCYTIC FUNCTION OF RETICULOENDOTHELIAL SYSTEM IN RATS TREATED WITH POLYBRENE LIQUOID AND COMPOUND 48/80

被引：4
作者：
LAZAR, G
BILICZKI, F
KOVACS, K
机构：
[1] Department of Pathophysiology, 1st Department of Medicine, University Medical School, Szeged
来源：
PHARMACOLOGY | 1968年 / 1卷 / 04期
关键词：
Compound; 48/80; Liquoid®; Polybrene®; RES Phagocytic function;
D O I：
10.1159/000135972
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The phagocytic function of the reticuloendothelial system was studied in rats by India ink clearance and histological examination. Twelve hours fol lowing Ihe intravenous administration of Polybrene or Liquoid the phagocytic activity of Ihe reticuloendothelial system in rats decreased, whereas after treatment with Compound 48/80 it remained unchanged. One hour after injection of Polybrene or Liquoid a significant amount of the intravenously administered India ink was lodged in Ihe lungs. Owing lo Ihe Inlrapulmonary India ink accumulation the phagocytic function of the HKS could not be evaluated at this period. © 1968 S. Karger AG, Basel.
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页码：253 / &
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