PREVENTION OF DEEP-VEIN THROMBOSIS BY LOW-MOLECULAR-WEIGHT HEPARIN AND DIHYDROERGOTAMINE IN PATIENTS UNDERGOING TOTAL HIP-REPLACEMENT

被引：17
作者：
FREICK, H [1 ]
HAAS, S [1 ]
机构：
[1] TECH UNIV MUNICH,INST EXPTL CHIRURG,W-8000 MUNICH 2,GERMANY
来源：
THROMBOSIS RESEARCH | 1991年 / 63卷 / 01期
关键词：
LOW-MOLECULAR-WEIGHT HEPARIN; DIHYDROERGOTAMINE; HEPARIN; DEEP VEIN THROMBOSIS; TOTAL HIP REPLACEMENT; POSTOPERATIVE THROMBOEMBOLISM;
D O I：
10.1016/0049-3848(91)90276-3
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
In 110 high-risk patients undergoing total hip replacement the antithrombotic efficacy and safety of a single daily injection of 1500 aPTT-U low-molecular-weight heparin plus 0,5 mg dihydroergotamine (Embolex(TM)) was, in a double-blind study, compared with a twice daily administration of 5000 IU of the heparin-dihydroergotamine combination Heparin-Dihydergot(TM). Deep vein thrombosis diagnosed with phlebography occurred in 9,6 % in the Embolex(TM)-group and in 25 % in the Heparin-Dihydergot(TM)-group. Intra- and post-operative blood loss and blood replacement were similar in both groups. Therefore, and on account of the single daily administration, Embolex(TM) offers at least the advantage of improved compliance of the patients and reduced workload of the nursing staff.
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页码：133 / 143
页数：11
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