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CLONING AND SEQUENCING OF THE CDNA-ENCODING HUMAN GLUTAREDOXIN
被引:21
作者:
FERNANDO, MR
SUMIMOTO, H
NANRI, H
KAWABATA, S
IWANAGA, S
MINAKAMI, S
FUKUMAKI, Y
TAKESHIGE, K
机构:
[1] UNIV OCCUPAT & ENVIRONM HLTH,DEPT HLTH DEV,KITAKYUSHU,JAPAN
[2] NAKAMURA GAUKEN UNIV,FUKUOKA,JAPAN
[3] KYUSHU UNIV,INST GENET INFORMAT,FUKUOKA 812,JAPAN
来源:
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
|
1994年
/
1218卷
/
02期
关键词:
GLUTAREDOXIN;
THIOLTRANSFERASE;
CDNA CLONING;
NUCLEOTIDE SEQUENCE;
(HUMAN);
D O I:
10.1016/0167-4781(94)90019-1
中图分类号:
Q5 [生物化学];
Q7 [分子生物学];
学科分类号:
071010 ;
081704 ;
摘要:
Glutaredoxin (thioltransferase) is a small, heat-stable protein, which is involved in thiol/disulfide exchange reactions. We have isolated a cDNA that encodes glutaredoxin from a human brain cDNA library. The encoded protein contains 106 amino acids with a calculated molecular mass of 11.76 kDa and an isoelectric point of 8.09. The amino acid sequence deduced from the cDNA is more than 80% identical to those of other mammalian glutaredoxins.
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页码:229 / 231
页数:3
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