BIMODAL SHAPE OF INDIVIDUAL VARIATION IN BEHAVIOR OF WISTAR RATS - THE OVERALL OUTCOME OF A FUNDAMENTALLY DIFFERENT MAKE-UP AND REACTIVITY OF THE BRAIN, THE ENDOCRINOLOGIC AND THE IMMUNOLOGICAL SYSTEM

被引：49

作者：

COOLS, AR ^{[1
]}

ROTS, NY ^{[1
]}

ELLENBROEK, B ^{[1
]}

DEKLOET, ER ^{[1
]}

机构：

[1] LEIDEN UNIV,CTR BIOPHARMACEUT SCI,SYLVIUS LAB,LEIDEN,NETHERLANDS

来源：

NEUROPSYCHOBIOLOGY | 1993年 / 28卷 / 1-2期

关键词：

SELECTIVE BREEDING; STRIATAL SYSTEM; LIMBIC SYSTEM; HYPOTHALAMIC-PITUITARY-ADRENAL SYSTEM; EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS; NEUROGENETICS; INDIVIDUAL VARIATION; APOMORPHINE;

D O I：

10.1159/000119009

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

An overview of the most important features of the two distinct types of individuals which normally co-occur in an unselected population of Wistar rats is given. It reveals that the overall make-up and reactivity of the brain, as well as the endocrinological and immunological systems differ completely between the two types of individuals. Each of these types of individuals has its own individual-specific hardware and software to cope with challenges from the internal or external environment, requires its own optimal niche, and is vulnerable for its own set of stressors.

引用

页码：100 / 105

页数：6

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