UNCOUPLING OF THE CYTOCHROME P-450CAM MONOOXYGENASE REACTION BY A SINGLE MUTATION, THREONINE-252 TO ALANINE OR VALINE - A POSSIBLE ROLE OF THE HYDROXY AMINO-ACID IN OXYGEN ACTIVATION

被引：363

作者：

IMAI, M

SHIMADA, H

WATANABE, Y

MATSUSHIMAHIBIYA, Y

MAKINO, R

KOGA, H

HORIUCHI, T

ISHIMURA, Y

机构：

[1] KEIO UNIV, SCH MED, DEPT BIOCHEM, TOKYO 160, JAPAN

[2] KYUSHU UNIV, FAC PHARMACEUT SCI, FUKUOKA 812, JAPAN

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1989年 / 86卷 / 20期

关键词：

D O I：

10.1073/pnas.86.20.7823

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：7823 / 7827

页数：5

共 34 条

[11]

Gunsalus I.C., 1974, MOL MECHANISMS OXYGE, P559

[12] CHLOROPEROXIDASE .9. STRUCTURE OF COMPOUND I [J].

HAGER, LP ;

HARGIS, JH ;

SILVERSTEIN, RM ;

MARTIN, JC ;

DOUBEK, DL .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1972, 94 (12) :4364-+

[13]

Hanahan D., 1985, DNA CLONING PRACTICA, P109

[14] OXYGENATED CYTOCHROME-P-450 AND ITS POSSIBLE ROLE IN ENZYMIC HYDROXYLATION [J].

ISHIMURA, Y ;

ULLRICH, V ;

PETERSON, JA .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1971, 42 (01) :140-&

[15] P450CAM GENE CLONING AND EXPRESSION IN PSEUDOMONAS-PUTIDA AND ESCHERICHIA-COLI [J].

KOGA, H ;

RAUCHFUSS, B ;

GUNSALUS, IC .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1985, 130 (01) :412-417

[16] THE GAPPED DUPLEX DNA APPROACH TO OLIGONUCLEOTIDE-DIRECTED MUTATION CONSTRUCTION [J].

KRAMER, W ;

DRUTSA, V ;

JANSEN, HW ;

KRAMER, B ;

PFLUGFELDER, M ;

FRITZ, HJ .

NUCLEIC ACIDS RESEARCH, 1984, 12 (24) :9441-9456

[17]

MAKINO R, 1986, J BIOL CHEM, V261, P1444

[18] REACTIONS OF SUPEROXIDE WITH IRON PORPHYRINS IN APROTIC-SOLVENTS - A HIGH-SPIN FERRIC PORPHYRIN PEROXO COMPLEX [J].

MCCANDLISH, E ;

MIKSZTAL, AR ;

NAPPA, M ;

SPRENGER, AQ ;

VALENTINE, JS ;

STONG, JD ;

SPIRO, TG .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1980, 102 (12) :4268-4271

[19]

OMURA T, 1962, J BIOL CHEM, V237, P1375

[20] THE MOLAR LIGHT ABSORPTION OF PYRIDINE FERROPROTOPORPHYRIN (PYRIDINE HAEMOCHROMOGEN) [J].

PAUL, KG ;

THEORELL, H ;

AKESON, A .

ACTA CHEMICA SCANDINAVICA, 1953, 7 (09) :1284-1287

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