COMPLEXATION STUDIES ON INOSITOL-PHOSPHATES .2. ALKALI-METAL COMPLEXES OF D-MYO-INOSITOL 1,2,6 TRISPHOSPHATE

被引：12

作者：

BIETH, H

SCHLEWER, G

SPIESS, B

机构：

[1] FAC PHARM STRASBOURG,CHIM ANALYT LAB,74 ROUTE RHIN,F-67401 ILLKIRCH GRAFFENS,FRANCE

[2] DEPT PHARMACOCHIM MOLEC,CNRS,CTR NEUROCHIM,STRASBOURG,FRANCE

来源：

JOURNAL OF INORGANIC BIOCHEMISTRY | 1991年 / 41卷 / 01期

关键词：

D O I：

10.1016/0162-0134(91)85007-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The complexation properties of the D-myo-inositol 1,2,6 trisphosphate (Ins(1,2,6)P3) towards Li+, Na+, K+, Rb+, and Cs+ cations were studied at 25-degrees-C in a 0.1 M tetra-n-butylammonium bromide medium. For all cations, mononuclear and protonated species were found. For smaller cations (Li+, Na+, and K+) a dinuclear complex was also put into evidence. The main characteristic of the complexes is its high stability; and of the ligand, its nonselectivity. The Ins(1,2,6)P3-K system was ascertained using Sammartano's method which additionally enabled the influence of various K+ concentrations on the protonations constants to be considered.

引用

页码：37 / 44

页数：8

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[2]

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