Phytochemical, In Vitro Antioxidant and Antimicrobial Activities in Aqueous and Methanol Extracts Of Chloroxylon Swietenia Bark

To investigate the phytochemical, in vitro antioxidant and antimicrobial activities in aqueous and methanol extracts of Chloroxylon swietenia bark. The antimicrobial activity was tested against bacteria as Staphylococcus aureus, Bacillus subtilis, Echerichia Coli, Klebsiella pneumonia, Pseudomonas aeruginosa and fungi as Candida albicans and Candida tropicalis. The antimicrobial activity was evaluated using disc diffusion methods. The in vitro antioxidant activity was carried out by DPPH, ABTS and hydrogen peroxide scavenging activities in aqueous and methanol extracts. The preliminary phytochemicals revealed that the presence of Tannins, Phenols, Glycosides, Phenolic compounds, Anthroquinones, Flavonoids. The antimicrobial activity of methanol extract of Chloroxylon swietenia bark was effective against tested organism as compared to aqueous extract. The free radical scavenging activity in methanol extract was found to be superior to aqueous extract. The obtained results concluded that the methanol extract of Chloroxylon swietenia bark possess potential antimicrobial and in vitro antioxidant activity as compared to aqueous extract. This activity might be attributed to the presence of phytochemicals in the plant.