ACTIVE SPECIFIC IMMUNOTHERAPY WITH TUMOR-CELLS AND CORYNEBACTERIUM-PARVUM - PHASE-I STUDY

被引：0

作者：

MCCUNE, CS

PATTERSON, WB

HENSHAW, EC

机构：

[1] UNIV ROCHESTER, SCH MED & DENT, DEPT MED, ROCHESTER, NY 14627 USA

[2] UNIV ROCHESTER, CTR CANC, ROCHESTER, NY 14627 USA

[3] UNIV ROCHESTER, SCH MED & DENT, DEPT SURG, ROCHESTER, NY 14627 USA

来源：

CANCER | 1979年 / 43卷 / 05期

关键词：

D O I：

10.1002/1097-0142(197905)43:5<1619::AID-CNCR2820430509>3.0.CO;2-O

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Autologous, irradiated (10,000 rads) tumor cells mixed with C. parvum [Propionibacterium acnes] were given as weekly intracutaneous injections to 15 patients with residual malignant disease. The toxicity was minimal and distinctly less than has been seen with tumor cell-BCG immunotherapy. A goal of 4 injections of 107 cells each was possible in only 4 patients because of limitations in methods of disaggregation and quantity of tumor available. The feasibility aspects are discussed and a case report of a prolonged regression is presented.

引用

页码：1619 / 1623

页数：5

共 17 条

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2-K

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