Differences in concentration of metal debris in blood, serum, and plasma samples of patients with metal-on-metal hip resurfacing arthroplasty

被引：6
作者：
Khan, M. [1 ]
Kuiper, J. H. [1 ]
Sieniawska, Christine [2 ]
Richardson, J. B. [1 ]
机构：
[1] Robert Jones & Agnes Hunt Orthopaed & Dist Hosp, Inst Orthopaed, Oswestry SY10 7AG, Shrops, England
[2] Univ Hosp Southampton NHS Fdn Trust, Dept Clin Biochem, Southampton SO16 6YD, Hants, England
来源：
JOURNAL OF ORTHOPAEDICS | 2016年 / 13卷 / 04期
关键词：
Metal ions; Serum; Plasma; Chromium; Cobalt;
D O I：
10.1016/j.jor.2015.10.006
中图分类号：
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];
学科分类号：
摘要：
Background/aims: Cobalt and chromium are released from MOM hips and their precise nature (ions/particles) is not known. Their distribution in serum, plasma, and whole blood may help to determine their nature. Methods: We measured cobalt and chromium concentrations in plasma, serum, and whole blood samples of patients with resurfacing MOM hips. Results: We found that chromium concentration was highest in plasma, followed by serum and whole blood. Chromium and cobalt concentrations were higher in serum and plasma, compared to whole blood. Conclusion: We, therefore, suggest that in future cobalt and chromium concentrations shall be reported using plasma samples. (C) 2015 Prof. PK Surendran Memorial Education Foundation. Published by Elsevier, a division of Reed Elsevier India, Pvt. Ltd. All rights reserved.
引用
收藏
页码：450 / 454
页数：5
相关论文
共 13 条
[1]   STATISTICAL METHODS FOR ASSESSING AGREEMENT BETWEEN TWO METHODS OF CLINICAL MEASUREMENT [J].
BLAND, JM ;
ALTMAN, DG .
LANCET, 1986, 1 (8476) :307-310
[2]   Consequences of exposure to peri-articular injections of micro- and nano-particulate cobalt-Chromium alloy [J].
Brown, Christopher ;
Lacharme-Lora, Lizeth ;
Mukonoweshuro, Blessing ;
Sood, Aman ;
Newson, Roger B. ;
Fisher, John ;
Case, C. Patrick ;
Ingham, Eileen .
BIOMATERIALS, 2013, 34 (34) :8564-8580
[3]   Size, shape, and composition of wear particles from metal-metal hip simulator testing: Effects of alloy and number of loading cycles [J].
Catelas, I ;
Bobyn, JD ;
Medley, JB ;
Krygier, JJ ;
Zukor, DJ ;
Huk, OL .
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2003, 67A (01) :312-327
[4]   The validity of serum levels as a surrogate measure of systemic exposure to metal ions in hip replacement [J].
Daniel, J. ;
Ziaee, H. ;
Pynsent, P. B. ;
McMinn, D. J. W. .
JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, 2007, 89B (06) :736-741
[5]   Renal Clearance of Cobalt in Relation to the Use of Metal-on-Metal Bearings in Hip Arthroplasty [J].
Daniel, Joseph ;
Ziaee, Hena ;
Pradhan, Chandra ;
Pynsent, Paul B. ;
McMinn, Derek J. W. .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 2010, 92A (04) :840-845
[6]  
Davies AP, 2005, J BONE JOINT SURG BR, V87B, P1439, DOI 10.1302/0301-620X.87B10
[7]  
Firkins PJ, 2001, BIO-MED MATER ENG, V11, P143
[8]   Can cobalt levels estimate in-vivo wear of metal-on-metal bearings used in hip arthroplasty? [J].
Khan, M. ;
Kuiper, J. H. ;
Richardson, J. B. .
PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE, 2007, 221 (H8) :929-942
[9]   Current in vivo wear of metal-on-metal bearings assessed by exercise-related rise in plasma cobalt level [J].
Khan, Munir ;
Takahashi, Tomoki ;
Kuiper, Jan H. ;
Sieniawska, Christine E. ;
Takag, Katsumasa ;
Richardson, James B. .
JOURNAL OF ORTHOPAEDIC RESEARCH, 2006, 24 (11) :2029-2035
[10]   Characterization of wear particles generated from CoCrMo alloy under sliding wear conditions [J].
Pourzal, R. ;
Catelas, I. ;
Theissmann, R. ;
Kaddick, C. ;
Fischer, A. .
WEAR, 2011, 271 (9-10) :1658-1666
12