KARYOTYPIC CHANGES IDENTIFIED BY HAEIII RESTRICTION ENDONUCLEASE BANDING IN A PATIENT WITH M2 ACUTE NONLYMPHOBLASTIC LEUKEMIA

被引：6

作者：

STUPPIA, L

PALKA, G

FIORITONI, G

CALABRESE, G

FRANCHI, PG

DARCANGELO, L

TORLONTANO, G

机构：

[1] UNIV CHIETI,CNR,INST CYTOMORPHOL,CHIETI,ITALY

[2] UNIV CHIETI,INST BIOL & GENET,CHIETI,ITALY

[3] UNIV CHIETI,INST HAEMATOL,CHIETI,ITALY

来源：

GENES CHROMOSOMES & CANCER | 1990年 / 1卷 / 04期

关键词：

D O I：

10.1002/gcc.2870010408

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A patient with acute non‐lymphoblastic leukemia, FAB type M2, showed a complex karyotype involving chromosomes 1 and 11. The breakpoints could not be exactly identified by GTG and QFQ banding. A subsequent analysis with AluI and HaeIII restriction enzyme staining allowed the detection of a translocation of the heterochromatic region of chromosome 1 to 11q21. Copyright © 1990 Wiley‐Liss, Inc., A Wiley Company

引用

页码：310 / 311

页数：2