2 NEOCLERODANE DITERPENOIDS CONTAINING AN UNUSUAL 2,6-DIOXABICYCLO[2.2.1]HEPTANE STRUCTURAL MOIETY

被引：20
作者：
DELATORRE, MC
BRUNO, M
PIOZZI, F
SAVONA, G
OMAR, AA
PERALES, A
RODRIGUEZ, B
机构：
[1] UNIV PALERMO, DIPARTMENTO CHIM ORGAN, ARCHIRAFI 20, I-90123 PALERMO, ITALY
[2] CSIC, INST QUIM ORGAN, E-28006 MADRID, SPAIN
[3] CSIC, INST ROCASOLANO, DEPT RAYOS X, E-28006 MADRID, SPAIN
[4] UNIV ALEXANDRIA, COLL PHARM, ALEXANDRIA, EGYPT
来源：
TETRAHEDRON | 1991年 / 47卷 / 20-21期
关键词：
D O I：
10.1016/S0040-4020(01)86408-5
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Two new diterpenoids, teucrolivins G and H, have been isolated from the aerial parts of Teucrium oliverianum (Labiatae). The structures of teucrolivin G [6-alpha,19-diacetoxy-4-alpha,18;15,16-diepoxy-3-oxo-neo-cleroda-13(16), 14-dien-12,8-beta,10-beta-acetal, 1] and teucrolivin H [19-acetoxy-4-alpha,18;15,16-diepoxy-6-alpha-hydroxy-3-oxo-neo-cleroda-13(16),14-dien-12,8-beta,10-beta-acetal, 2] were established mainly by spectroscopic means, including an x-ray diffraction analysis of the former (1). Compounds 1 and 2 possess an unusual 2,6-dioxabicyclo [2.2.1] heptane structural moiety which, to the best of our knowledge, has now been found for the first time in natural products.
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页码：3463 / 3470
页数：8
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