AN ISFET-BASED FLOW-INJECTION ANALYSIS SYSTEM FOR DETERMINATION OF UREA - EXPERIMENT AND THEORY

被引：12
作者：
CHANDLER, GK
DODGSON, JR
EDDOWES, MJ
机构：
[1] Thorn EMI Central Research Laboratories, Hayes, Middlesex UB3 1HH, Dawley Road
来源：
SENSORS AND ACTUATORS B-CHEMICAL | 1990年 / 1卷 / 1-6期
关键词：
D O I：
10.1016/0925-4005(90)80244-T
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Preliminary work is presented on an ISFET-based flow injection analysis system for urea determination, which avoids the need for compromise between speed of response and sensitivity found in integrated EnFETs. The response is linear for 30 μl samples in the range 0-25 mM urea; the response time is around 30 s. Theory which calculates the distribution of protons between the various buffers present, assuming 100% conversion of urea, gives a good description of the response and allows optimisation of the system to reduce interference by sample buffer and pH variations. © 1990.
引用
收藏
页码：433 / 437
页数：5
相关论文
共 9 条
[1]   COULOMETRIC FLOW ANALYZER FOR USE WITH IMMOBILIZED ENZYME REACTORS [J].
ADAMS, RE ;
CARR, PW .
ANALYTICAL CHEMISTRY, 1978, 50 (07) :944-950
[2]   PH-BASED ENZYME POTENTIOMETRIC SENSORS .1. THEORY [J].
CARAS, SD ;
JANATA, J ;
SAUPE, D ;
SCHMITT, K .
ANALYTICAL CHEMISTRY, 1985, 57 (09) :1917-1920
[3]   ENZYME-MEDIATED PH-SENSITIVE FET DEVICES - PROBLEMS OF THE NON-LINEAR RESPONSE [J].
CHANDLER, GK ;
EDDOWES, MJ .
SENSORS AND ACTUATORS, 1988, 13 (03) :223-228
[4]   RESPONSE OF AN ENZYME-MODIFIED PH-SENSITIVE ION-SELECTIVE DEVICE - ANALYTICAL SOLUTION FOR THE RESPONSE IN THE PRESENCE OF PH BUFFER [J].
EDDOWES, MJ .
SENSORS AND ACTUATORS, 1987, 11 (03) :265-274
[5]   A FLOW-INJECTION SYSTEM BASED ON IMMOBILIZED PENICILLINASE AND A LINEAR PH-BUFFER FOR POTENTIOMETRIC DETERMINATION OF PENICILLIN [J].
OLSSON, B .
ANALYTICA CHIMICA ACTA, 1988, 209 (1-2) :123-133
[6]   ENZYMATIC DETERMINATION OF UREA IN SERUM BASED ON PH MEASUREMENT WITH THE FLOW INJECTION METHOD [J].
RUZICKA, J ;
HANSEN, EH ;
GHOSE, AK ;
MOTTOLA, HA .
ANALYTICAL CHEMISTRY, 1979, 51 (02) :199-203
[7]  
STUMM W, 1974, AQUAT CHEM, P88
[8]  
VANDERSCHOOT BH, 1987, BIOSENSORS, V3, P161
[9]  
WEETALL HH, 1976, METHOD ENZYMOL, V44, pCH10
1