DIRECT DEMONSTRATION OF SUPEROXIDE ANION PRODUCTION DURING OXIDATION OF REDUCED FLAVIN AND OF ITS CATALYTIC DECOMPOSITION BY ERYTHROCUPREIN

被引：217
作者：
BALLOU, D
PALMER, G
MASSEY, V
机构：
[1] Department of Biological Chemistry, University of Michigan, Ann Arbor, MI
[2] Biophysics Research Division Institute of Science and Technology, University of Michigan, Ann Arbor, MI
来源：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1969年 / 36卷 / 06期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1016/0006-291X(69)90288-5
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The oxidation of reduced flavins by molecular oxygen at neutral to alkaline pH produces substantial yields of the superoxide anion, O2•. This species is rapidly destroyed by catalytic quantities of the copper protein, erythrocuprein, and by stoichiometric quantities of ferricytochrome c. © 1969.
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页码：898 / &
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