A CONVENIENT AND FACILE SYNTHESIS OF 5-TRIFLUOROMETHYL-1,2,4-TRIAZINE DERIVATIVES

被引：0
|
作者：
KAMITORI, Y
HOJO, M
MASUDA, R
SUKEGAWA, M
HAYASHI, K
KOUZEKI, K
机构：
来源：
HETEROCYCLES | 1994年 / 39卷 / 01期
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D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
3-Hydrazono-1,1,1 -trifluoroalkan-2-ones (2) and 3-methylydrazono-1,1,1-trifluoroalkan-2-ones (3) prepared from 1,1,1-trifluoroalkane-2,3-diones (1) reacted with several aldehydes in the presence of aq. NH4OH to afford 5-trifluoromethyl-2,3-dihydro-1 ,2,4-triazines (4 and 5) of which oxidation gave 5-trifluoromethyl-1,2,4-triazines (6) and 5-trifluoromethyl-2,5-dihydro-5-hydroxy-1,2,4-triazines (7). Thermal reaction of 5 afforded 1-amino-4-trifluoromethylimidazores (8).
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页码：155 / 162
页数：8
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