EFFECT OF NEONATAL BLOOD-SERUM ON THE EARLY STAGES OF MOUSE EMBRYOGENESIS IN-VITRO

被引：0

作者：

ARKHANGELSKAYA, IB

SHTILBANS, VI

CHEBOTAR, NA

KOTIN, AM

机构：

[1] Department of Molecular Genetics, Institute of Experimental Medicine, Russian Academy of Medical Sciences, St. Petersburg

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 1994年 / 118卷 / 07期

关键词：

EMBRYO; EMBRYOTOXIC EFFECT; NEWBORN;

D O I：

10.1007/BF02444355

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The effect of blood sera from newborns delivered after complicated pregnancy and abnormal labor (CPAL) on 4-cell mouse embryos is studied, The embryos develop normally in the control sera, 78-100% of them reach the blastocyst stage, the mean number of blastomeres per embryo varies from 68 to 88 cells, and the mortality rate is 3-7%. The CPAL sera have an almost 100% embryolethal effect. The development of mouse embryos is markedly delayed. The most potent pathological effect is elicited by the sera of newborns whose mothers suffered from hypoxia.

引用

页码：683 / 685

页数：3