CUTANEOUS HEMANGIOSARCOMA IN 25 DOGS - A RETROSPECTIVE STUDY

被引:98
作者
WARD, H [1 ]
FOX, LE [1 ]
CALDERWOODMAYS, MB [1 ]
HAMMER, AS [1 ]
COUTO, CG [1 ]
机构
[1] OHIO STATE UNIV,DEPT VET CLIN SCI,601 VERNON L THARP,COLUMBUS,OH 43210
关键词
D O I
10.1111/j.1939-1676.1994.tb03248.x
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Hemangiosarcomas confined to the skin and underlying muscle were surgically excised in 25 dogs. Tumors were staged based on their histological location (ie, dermal, hypodermal, and deep). Dermal (stage I) hemangiosarcomas were small, most commonly ventral-abdominal or prepucial in location, and were associated with prolonged survival times (median survival, 780 days). Tumors with hypodermal (stage II) and underlying muscular involvement (stage III) were grouped together because of their larger size, bruise-like appearance, lack of anatomic predilection, biological behavior, and shorter survival times (median survival of 172 and 307 days for dogs with stages II and III, respectively). We conclude that dermal hemangiosarcomas may be effectively treated with surgery alone, whereas hemangiosarcomas located within the hypodermal tissues bear a poor prognosis and warrant wide surgical excision with adjuvant chemotherapy.
引用
收藏
页码:345 / 348
页数:4
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  • [1] Moulton JE., Tumors in Domestic Animals, pp. 35-36, (1978)
  • [2] Oksanen A., Haemangiosarcoma in dogs, J Comp Pathol, 88, pp. 585-595, (1978)
  • [3] Prymak C., McKee LJ, Goldschmidt MH, Et al., Epidemiologic, clinical, pathologic, and prognostic characteristics of splenic hemangiosarcoma and splenic hematoma in dogs: 217 cases (1985), J Am Vet Med Assoc, 193, pp. 706-712, (1988)
  • [4] Waller T., Rubarth S., Hemangioendothelioma in domestic animals, Acta Vet Scand, 8, pp. 234-261, (1967)
  • [5] Ng CY, Mills JN., Clinical and haematological features of haemangiosarcoma in dogs, Aust Vet J, 62, pp. 1-4, (1985)
  • [6] Pearson GR, Head KW., Malignant haemangioendothelioma (angiosarcoma) in the dog, J Small Anim Pract, 17, pp. 737-745, (1976)
  • [7] Brown NO, Patnaik AK, MacEwen EG., Canine hemangiosarcoma: Retrospective analysis of 104 cases, J Am Vet Med Assoc, 186, pp. 56-58, (1985)
  • [8] Hirsch VM, Jacobsen J., Mills JH., A retrospective study of canine hemangiosarcoma and its association with acanthocytosis, Can VetJ, 22, pp. 152-155, (1981)
  • [9] Hammer AS, Couto CG., Diagnosing and treating canine hemangiosarcoma, Vet Med, 87, pp. 188-192, (1992)
  • [10] Bevier DE, Goldschmidt MH., Skin tumors in the dog. Part II. Tumors of the soft (mesenchymal) tissues, Comp Cont Ed, 6, pp. 506-516, (1981)