BIOCHEMICAL PATHOLOGY AND TREATMENT STRATEGIES IN ALZHEIMERS-DISEASE - EMPHASIS ON THE CHOLINERGIC SYSTEM

被引:0
作者
WINBLAD, B
MESSAMORE, E
ONEILL, C
COWBURN, R
机构
来源
ACTA NEUROLOGICA SCANDINAVICA | 1993年 / 88卷
关键词
ALZHEIMERS DISEASE; CHOLINERGIC HYPOTHESIS; TREATMENT STRATEGIES;
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The neurochemical pathology of Alzheimer's disease (AD) has been consistently shown to involve cholinergic degeneration in the cerebral cortex. This together with evidence from experimental animal studies showing that cholinergic neurones play a role in learning and memory processes has formed the basis of the cholinergic hypothesis of Alzheimer's dementia and the major rationale for neurotransmitter replacement therapy of the disorder.
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页码:4 / 6
页数:3
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