Oral Inflammatory Myofibroblastic Tumor: Case Report and Review of Literature

被引：17

作者：

Binmadi, Nada O. ^{[1
]}

Packman, Harold

Papadimitriou, John C. ^{[2
]}

Scheper, Mark ^{[1
]}

机构：

[1] Univ Maryland, Dent Sci, Dept Oncol & Diagnost Sci, Baltimore, MD 21201 USA

[2] Univ Maryland, Baltimore Sch Med, Dept Pathol, Baltimore, MD 21201 USA

来源：

OPEN DENTISTRY JOURNAL | 2011年 / 5卷

关键词：

Inflammatory myofibroblastic tumor; inflammatory pseudotumor; oral cavity;

D O I：

10.2174/1874210601105010066

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Inflammatory myofibroblastic tumor (IMT) is a rarely described tumor of unknown etiology and pathogenesis. It occurs primarily in the lungs, but has occurred in other extra-pulmonary sites. Histologically these lesions appear as an inflammatory infiltrate within a variably myofibrotic background. Current evidence shows that inflammatory myofibroblastic tumors are neoplastic processes resulting from chromosomal translocations that often cause an overexpression of ALK kinase, which is often assessed using immunohistochemical studies. Currently, the biological behavior of oral inflammatory myofibroblastic tumor is still uncertain. This article describes the clinical, histological, and operative features of a case of IMT of the oral cavity.

引用

页码：66 / 70

页数：5

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