Determination of migratory organotin compounds in toys by headspace-solid phase microextraction coupled with gas chromatography. mass spectrometry

A method for the determination of ten migratory organotin compounds in toys was developed using headspace-solid phase microextraction (HS-SPME) coupled with gas chromatography-mass spectrometry (GC-MS) . Toy materials were soaked in 0.07 mol/L HCl for 2 h, then the pH of the soak solution was adjusted to 4.7 by HAc-NaAc buffer-After ethylized with sodium tetraethylborate (NaBEt4), the soaked solution was agitated and the headspace solid phase microextraction was performed with a 100 mu m polydimethylsiloxane (PDMS) fiber. After extraction, the SPME fiber was directly injected into the GC inlet, and the organotin compounds were separated on a DB-5 capillary column. The limits of detection for the ten organotin compounds were in the range of 0.5-5 mu g/kg. The recoveries were in the ranges of 80.7%-118.7% and 86.2%-120.5% at the spiked levels of 0.500 mu g/L and 5.00 mu g /L. The relation standard deviations (RSDs) were all less than 15%. This method has been used to determine migratory organotin in accessible parts of toys, including coating, plastic, wood and textile. The method is simple, fast, sensitive and solvent-free.