Gestational diabetes: A clinical update

被引:200
作者
Kampmann, Ulla [1 ]
Madsen, Lene Ring [1 ]
Skajaa, Gitte Oeskov [2 ]
Iversen, Ditte Smed [2 ]
Moeller, Niels [1 ]
Ovesen, Per [2 ]
机构
[1] Aarhus Univ Hosp, Dept Endocrinol & Internal Med, DK-8000 Aarhus, Denmark
[2] Aarhus Univ Hosp, Dept Obstet & Gynecol, DK-8000 Aarhus, Denmark
关键词
Gestational diabetes; Diagnostic criteria; Treatment; Complications;
D O I
10.4239/wjd.v6.i8.1065
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Gestational diabetes mellitus (GDM) is increasing in prevalence in tandem with the dramatic increase in the prevalence of overweight and obesity in women of childbearing age. Much controversy surrounds the diagnosis and management of gestational diabetes, emphasizing the importance and relevance of clarity and consensus. If newly proposed criteria are adopted universally a significantly growing number of women will be diagnosed as having GDM, implying new therapeutic challenges to avoid foetal and maternal complications related to the hyperglycemia of gestational diabetes. This review provides an overview of clinical issues related to GDM, including the challenges of screening and diagnosis, the pathophysiology behind GDM, the treatment and prevention of GDM and the long and short term consequences of gestational diabetes for both mother and offspring.
引用
收藏
页码:1065 / 1072
页数:8
相关论文
共 68 条
[1]   Animal evidence for the transgenerational development of diabetes mellitus [J].
Aerts, L ;
Van Assche, FA .
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2006, 38 (5-6) :894-903
[2]   Diagnostic criteria and classification of hyperglycaemia first detected in pregnancy: A World Health Organization Guideline [J].
Agarwal, Mukesh M. ;
Boulvain, Michel ;
Coetzee, Edward ;
Colagiuri, Stephen ;
Falavigna, Maicon ;
Hod, Moshe ;
Meltzer, Sara ;
Metzger, Boyd ;
Omori, Yasue ;
Rasa, Ingvars ;
Schmidt, Maria Ines ;
Seshiah, Veerasamy ;
Simmons, David ;
Sobngwi, Eugene ;
Torloni, Maria Regina ;
Yang, Huixia ;
Balaji, V. ;
Mendis, Shanthi P. B. ;
Roglic, Gojka ;
Merialdi, Mario ;
Betran, Ana Pilar ;
Jenum, Anne Karen ;
Lao, Terence ;
Lopez Stewart, Gloria ;
Mikhailov, Anton ;
Moses, Robert ;
Samad, Noorjahan .
DIABETES RESEARCH AND CLINICAL PRACTICE, 2014, 103 (03) :341-363
[3]   Role of Vitamin D in Insulin Secretion and Insulin Sensitivity for Glucose Homeostasis [J].
Alvarez, Jessica A. ;
Ashraf, Ambika .
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY, 2010, 2010
[4]   Standards of Medical Care in Diabetes-2014 [J].
不详 .
DIABETES CARE, 2014, 37 :S14-S80
[5]   Physical Activity and Sedentary Behaviors Associated With Risk of Progression From Gestational Diabetes Mellitus to Type 2 Diabetes Mellitus A Prospective Cohort Study [J].
Bao, Wei ;
Tobias, Deirdre K. ;
Bowers, Katherine ;
Chavarro, Jorge ;
Vaag, Allan ;
Grunnet, Louise Groth ;
Strom, Marin ;
Mills, James ;
Liu, Aiyi ;
Kiely, Michele ;
Zhang, Cuilin .
JAMA INTERNAL MEDICINE, 2014, 174 (07) :1047-1055
[6]   Cellular mechanisms for insulin resistance in normal pregnancy and gestational diabetes [J].
Barbour, Linda A. ;
McCurdy, Carrie E. ;
Hernandez, Teri L. ;
Kirwan, John P. ;
Catalano, Patrick M. ;
Friedman, Jacob E. .
DIABETES CARE, 2007, 30 :S112-S119
[7]   Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis [J].
Bellamy, Leanne ;
Casas, Juan-Pablo ;
Hingorani, Aroon D. ;
Williams, David .
LANCET, 2009, 373 (9677) :1773-1779
[8]   Epidemiology of gestational diabetes mellitus and its association with Type 2 diabetes [J].
Ben-Haroush, A ;
Yogev, Y ;
Hod, M .
DIABETIC MEDICINE, 2004, 21 (02) :103-113
[9]   RACE ETHNICITY AND OTHER RISK-FACTORS FOR GESTATIONAL DIABETES [J].
BERKOWITZ, GS ;
LAPINSKI, RH ;
WEIN, R ;
LEE, D .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 1992, 135 (09) :965-973
[10]   Insulin Requirements in Type 1 Diabetic Pregnancy Do twin pregnant women require twice as much insulin as singleton pregnant women? [J].
Callesen, Nicoline F. ;
Ringholm, Lene ;
Stage, Edna ;
Damm, Peter ;
Mathiesen, Elisabeth R. .
DIABETES CARE, 2012, 35 (06) :1246-1248