ADENOVIRUS SEROTYPE-1 DOES NOT ACT SYNERGISTICALLY WITH MORAXELLA (BRANHAMELLA) CATARRHALIS TO INDUCE OTITIS-MEDIA IN THE CHINCHILLA

被引：34
作者：
BAKALETZ, LO
MURWIN, DM
BILLY, JM
机构：
来源：
INFECTION AND IMMUNITY | 1995年 / 63卷 / 10期
关键词：
D O I：
10.1128/IAI.63.10.4188-4190.1995
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
A chinchilla model of otitis media in which adenovirus compromise of the tubotympanum facilitates the subsequent induction of middle ear disease was used to investigate Moraxella (Branhamella) catarrhalis pathogenesis. Intranasally inoculated M. catarrhalis did readily colonize the nasopharynx of this host; however, despite evidence of viral infection and tubotympanal compromise, M. catarrhalis did not induce culture-positive otitis media in this model.
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页码：4188 / 4190
页数：3
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