COLICIN-A AND COLICIN-E1 LYSIS PROTEINS DIFFER IN THEIR DEPENDENCE ON SECA AND SECY GENE-PRODUCTS

被引：8

作者：

CAVARD, D

机构：

[1] Centre de Biochimie et de Biologie, Moléculaire du C.N.R.S., 13402 Marseille Cedex 9, 31 Chemin Joseph Alguier

来源：

FEBS LETTERS | 1992年 / 298卷 / 01期

关键词：

LYSIS PROTEIN; COLICIN; SECA PROTEIN; SECY PROTEIN; PROTEIN SECRETION; ESCHERICHIA-COLI;

D O I：

10.1016/0014-5793(92)80027-E

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The export of colicin A and of colicin E1 is not equally affected in both secA and secY mutants of Escherichia coli: release of colicin A occurs slowly while that of colicin E1 is blocked. Processing and functioning of Cal, the colicin A lysis protein, seem to be slightly or not at all modified in these mutants. whereas synthesis and assembly of CelA, the colicin E1 lysis protein, are highly inhibited. These variations observed in the dependence of the two lysis proteins on secA and secY gene products are interpreted as being either the cause or the consequence of the differences observed in their rate of biogenesis,

引用

页码：84 / 88

页数：5

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