THE PLATELET COUNT AS A SIMPLE MEASURE TO DISTINGUISH INFLAMMATORY BOWEL-DISEASE FROM INFECTIVE DIARRHEA

被引:40
作者
HARRIES, AD
BEECHING, NJ
ROGERSON, SJ
NYE, FJ
机构
[1] Regional Infectious Disease Unit, Fazakerley Hospital, Liverpool, L9 7AL, Longmoor Lane
关键词
D O I
10.1016/S0163-4453(05)80006-4
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
A total of 212 adult patients with infective diarrhoea and 27 with inflammatory bowel disease (IBD), admitted consecutively to an infectious disease unit, were studied in order to determine whether clinical features and laboratory measurements performed on admission identified cases of IBD. Long-standing diarrhoea, blood in the faeces, anaemia, leucocytosis, thrombocytosis, raised ESR and a reduced concentration of serum albumin were more common in patients with IBD (P < 0.05). The most striking difference was in the platelet count with 59% patients with IBD and 1·6% patients with infective diarrhoea having platelet counts > 450 × 109/1. A raised platelet count in a patient admitted to hospital with 'acute gastro-enteritis' suggests IBD. © 1991 The British Society for the Study of Infection.
引用
收藏
页码:247 / 250
页数:4
相关论文
共 50 条
[41]   INVITRO AND INVIVO PLATELET HYPERAGGREGABILITY IN INFLAMMATORY BOWEL-DISEASE (IBD) [J].
COLLINS, CE ;
CAHILL, MR ;
NEWLAND, AC ;
RAMPTON, DS .
BRITISH JOURNAL OF HAEMATOLOGY, 1993, 84 :55-55
[42]   COAGULATION AND PLATELET ABNORMALITIES IN ACUTE, UNTREATED INFLAMMATORY BOWEL-DISEASE [J].
LAKE, AM ;
STAUFFER, JQ ;
STUART, MJ .
GASTROENTEROLOGY, 1976, 70 (05) :905-905
[43]   CLOSTRIDIUM-DIFFICILE ASSOCIATED DIARRHEA - ROLE IN INFLAMMATORY BOWEL-DISEASE [J].
BOLTON, RP ;
SHERRIFF, RJ ;
READ, AE .
GUT, 1979, 20 (10) :A932-A933
[44]   DEVASTATING DIARRHEA CAUSED BY AZATHIOPRINE - MANAGEMENT DIFFICULTY IN INFLAMMATORY BOWEL-DISEASE [J].
COX, J ;
DANESHMEND, TK ;
HAWKEY, CJ ;
LOGAN, RFA ;
WALT, RP .
GUT, 1988, 29 (05) :686-688
[45]   INFECTIOUS CAUSES OF DIARRHEA IN THE DIFFERENTIAL-DIAGNOSIS OF INFLAMMATORY BOWEL-DISEASE [J].
FARMER, RG .
MEDICAL CLINICS OF NORTH AMERICA, 1990, 74 (01) :29-38
[46]   INCREASED PLATELET-AGGREGATION IN INFLAMMATORY BOWEL-DISEASE (IBD) [J].
COLLINS, CE ;
CAHILL, MR ;
SYNDERCOMBECOURT, D ;
RAMPTON, DS .
GASTROENTEROLOGY, 1993, 104 (04) :A684-A684
[47]   PLATELET COUNT - A SIMPLE MEASURE OF ACTIVITY IN CROHNS-DISEASE [J].
HARRIES, AD ;
FITZSIMONS, E ;
FIFIELD, R ;
DEW, MJ ;
RHODES, J .
BRITISH MEDICAL JOURNAL, 1983, 286 (6376) :1476-1476
[48]   Incorporating platelet count to differentiate flares of inflammatory bowel disease and infectious gastroenteritis in patients admitted to hospital with diarrhea [J].
Gazelakis, K. ;
Ward, M. ;
Chu, I. ;
Sparrow, M. .
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2020, 35 :131-132
[49]   FREQUENCY OF INFLAMMATORY BOWEL-DISEASE IN OFFSPRING OF COUPLES BOTH PRESENTING WITH INFLAMMATORY BOWEL-DISEASE [J].
BENNETT, RA ;
RUBIN, PH ;
PRESENT, DH .
GASTROENTEROLOGY, 1991, 100 (06) :1638-1643
[50]   INFLAMMATORY INTERMEDIARIES IN INFLAMMATORY BOWEL-DISEASE [J].
LAURITSEN, K ;
LAURSEN, LS ;
BUKHAVE, K ;
RASKMADSEN, J .
INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 1989, 4 (02) :75-90