A 45-year-old woman with adult T-cell leukemia had a sudden onset of decreased vision with central scotoma in the right eye. Right optic disc edema and thickening of the optic nerve were observed by magnetic resonance imaging. A diagnosis of leukemic infiltration to the optic nerve was made. A course of oral corticosteroid therapy was prescribed and 40 Gy of radiation was administered to the whole brain and right orbit. Her visual acuity recovered from finger counting to 20/20 within 3 weeks. We believe that this patient represents the first report of successfully treated optic nerve infiltration with adult T-cell leukemia caused by human T-lymphotropic virus type-I infection.
机构:
Royal Marsden NHS Trust, Inst Canc Res, Haematol Oncol Unit, London SW3 6JJ, EnglandRoyal Marsden NHS Trust, Inst Canc Res, Haematol Oncol Unit, London SW3 6JJ, England
机构:
Iwate Med Univ, Dept Internal Med, Div Hepatol, Morioka, Iwate, JapanIwate Med Univ, Dept Internal Med, Div Hepatol, Morioka, Iwate, Japan
Kakisaka, Keisuke
Suzuki, Yuji
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Iwate Med Univ, Dept Internal Med, Div Hepatol, Morioka, Iwate, JapanIwate Med Univ, Dept Internal Med, Div Hepatol, Morioka, Iwate, Japan
Suzuki, Yuji
Kowata, Shugo
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Iwate Med Univ, Dept Internal Med, Div Hematol & Malignancy, Morioka, Iwate, JapanIwate Med Univ, Dept Internal Med, Div Hepatol, Morioka, Iwate, Japan
Kowata, Shugo
Ito, Shigeki
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Iwate Med Univ, Dept Internal Med, Div Hematol & Malignancy, Morioka, Iwate, JapanIwate Med Univ, Dept Internal Med, Div Hepatol, Morioka, Iwate, Japan
Ito, Shigeki
Takikawa, Yasuhiro
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Iwate Med Univ, Dept Internal Med, Div Hepatol, Morioka, Iwate, JapanIwate Med Univ, Dept Internal Med, Div Hepatol, Morioka, Iwate, Japan