A Case of Plasmodium vivax Malaria with Cerebral Complication

被引：1

作者：

Kim, Moonsuk ^{[1
]}

Kim, Gayeon ^{[1
]}

Kang, Yumin ^{[1
]}

Kim, Nak-Hyun ^{[1
]}

Jeon, Jae Hyun ^{[1
]}

Park, Wan Beom ^{[1
]}

Kim, Hong Bin ^{[1
]}

Kim, Nam Joong ^{[1
]}

Park, Sang-Won ^{[1
]}

Hong, Yoon-Ho ^{[2
]}

Oh, Myoung-don ^{[1
]}

机构：

[1] Seoul Natl Univ, Coll Med, Dept Internal Med, Seoul, South Korea

[2] Boramae Med Ctr, Dept Neurol, Seoul, South Korea

来源：

INFECTION AND CHEMOTHERAPY | 2009年 / 41卷 / 05期

关键词：

Plasmodium vivax; Cerebral malaria; Korea;

D O I：

10.3947/ic.2009.41.5.309

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Plasmodium vivax malaria is an endemic disease in Korea, which rarely causes severe complications including those occurring in the cerebrum. There are limited numbers of complicated cases that have been reported around the world. We experienced a case of vivax malaria with cerebral complication: cognitive impairment and ataxia. A 55-year-old female with diabetes mellitus presented to the emergency department with acute fever of two days' duration. She did not have any history of travelling abroad or receiving blood transfusions. Peripheral blood smear revealed vivax malaria with parasitemia density of 0.53 percent. She demonstrated loss of orientation, especially regarding time and place, and ataxia. Although the initial hydroxychloroquine treatment for malaria was successful, cognitive impairment and ataxia persisted and were not recovered. Brain MRI showed no structural abnormality. Brain PET showed diffuse hypometabolism in right parieto-temporal lobe of the brain.

引用

页码：309 / 313

页数：5

共 17 条

[1]

Beales PF, 2000, T ROY SOC TROP MED H, V94, pS1

[2] Cerebral involvement in benign tertian malaria [J].

Beg, MA ;

Khan, R ;

Baig, SM ;

Gulzar, Z ;

Hussain, R ;

Smego, RA .

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2002, 67 (03) :230-232

[3] Deficits in delayed memory following cerebral malaria: A case study [J].

Grote, CL ;

PierreLouis, SJC ;

Durward, WF .

CORTEX, 1997, 33 (02) :385-388

[4] Pathogenesis, clinical features, and neurological outcome of cerebral malaria [J].

Idro, R ;

Jenkins, NE ;

Newton, CRJC .

LANCET NEUROLOGY, 2005, 4 (12) :827-840

[5] A Case of Myocarditis Associated With Plasmodium vivax Malaria [J].

Kim, Soon Ae ;

Kim, Eu Suk ;

Rhee, Moo Yong ;

Choi, Sang Il ;

Huh, Hee Jin ;

Chae, Seok Lae .

JOURNAL OF TRAVEL MEDICINE, 2009, 16 (02) :138-140

[6]

Kochar D K, 2002, J Assoc Physicians India, V50, P234

[7]

Korea Center for Disease Control and Prevention, STAT INF DIS

[8] Diagnosis and management of the neurological complications of falciparum malaria [J].

Mishra, Saroj K. ;

Newton, Charles R. J. C. .

NATURE REVIEWS NEUROLOGY, 2009, 5 (04) :189-198

[9] Cerebral malaria owing to Plasmodium vivax:: case report [J].

Ozen, Metehan ;

Gungor, Serdal ;

Atambay, Metin ;

Daldal, Nilgun .

ANNALS OF TROPICAL PAEDIATRICS, 2006, 26 (02) :141-144

[10] Adult cerebral malaria: Prognostic importance of imaging findings and correlation with postmortem findings [J].

Patankar, TF ;

Karnad, DR ;

Shetty, PG ;

Desai, AP ;

Prasad, SR .

RADIOLOGY, 2002, 224 (03) :811-816

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