THE EFFECT OF ZIDOVUDINE ON NEUROPSYCHIATRIC MEASURES IN HIV-INFECTED MEN

被引：0
作者：
GORMAN, JM
MAYEUX, R
STERN, Y
WILLIAMS, JBW
RABKIN, J
GOETZ, RR
EHRHARDT, AA
机构：
[1] COLUMBIA UNIV COLL PHYS & SURG,DEPT PSYCHIAT,NEW YORK,NY 10032
[2] COLUMBIA UNIV COLL PHYS & SURG,DEPT NEUROL,NEW YORK,NY 10032
来源：
AMERICAN JOURNAL OF PSYCHIATRY | 1993年 / 150卷 / 03期
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D O I：
暂无
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
The authors examined the effects of zidovudine on neuropsychiatric measures, at three assessment points separated by 6 months, in 25 HIV-positive men who took zidovudine for at least 6 months and a comparison group of 25 HIV-positive men with similar CD4+ T cell counts who bad never taken zidovudine. Zidovudine had no statistically significant effect except for a slight improvement in Global Assessment of Functioning scale score. In this small group of subjects there was little benefit but also little evidence of CNS toxicity from zidovudine.
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页码：505 / 507
页数：3
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