MUSCULAR DYSTROPHY AND OTHER MYOPATHIES - SARCOTUBULAR VESICLES IN EARLY DISEASE

被引：69

作者：

PETER, JB

WORSFOLD, M

机构：

[1] Department of Medicine, UCLA School of Medicine, Los Angeles

来源：

BIOCHEMICAL MEDICINE | 1969年 / 2卷 / 05期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0006-2944(69)90040-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Sarcotubular vesicles from patients with certain types of muscular dystrophy or polymyositis show a diminished ability to remove calcium from very dilute solutions (decreased calcium affinity), whereas in some of these patients the capacity of vesicles to accumulate calcium, in the presence of excess calcium, is normal. Decreased calcium affinity is detectable in these disorders when oxidative phosphorylation of concomitantly isolated mitochondria is normal. It is not found in a wide variety of other muscular or neuromuscular diseases. © 1969.

引用

页码：364 / &

共 15 条

[1] ACTIVITES ENZYMATIQUES DU MUSCLE HUMAIN - RECHERCHES SUR LA BIOCHIMIE COMPAREE DE LHOMME NORMAL ET MYOPATHIQUE, ET DU RAT [J].