OLIGOSACCHARIDE COMPONENT IN PROTEOGLYCANS OF ARTICULAR-CARTILAGE

被引:48
作者
THONAR, EJMA
SWEET, MBE
机构
[1] Orthopaedic Research Laboratories, Department of Orthopaedic Surgery, University of the Witwatersrand, Johannesburg
关键词
(Articular cartilage); Oligosaccharide; Proteoglucan;
D O I
10.1016/0304-4165(79)90281-2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Two types of sialic acid-containing component are released from articular cartilage proteoglycan monomer (D1) treated with 0.05 M NaOH containing 1 M NaBH4. The smaller component, which has not been described before, contains galactosamine, glucosamine, galactose and sialic acid (Molar ratio 1:1:1:2). It is eluted from ECTEOLA-cellulose with low molarity (0.4 M) sodium formate and has a Kav of 0.70 on Bio-gel P30. Its presence on the proteoglycan monomer was demonstrated at all stages of foetal and adult life. © 1979.
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页码:353 / 357
页数:5
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