TITANOCENE DICHLORIDE - 1ST METALLOCENE WITH CANCEROSTATIC ACTIVITY

被引:259
作者
KOPF, H [1 ]
KOPFMAIER, P [1 ]
机构
[1] FREE UNIV BERLIN,INST ANAT,D-1000 BERLIN 33,FED REP GER
来源
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1979年 / 18卷 / 06期
关键词
D O I
10.1002/anie.197904771
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The cancerostatic activity of metal complexes can be tested on mice by injection of tumor cells and, 24 h later, the substance to be investigated. Compound 1, selected partly because of its structural similarity to the antitumor agent 2, exhibited a cure rate of over 80% in the therapeutic range. (Figure Presented.) Copyright © 1979 by Verlag Chemie, GmbH, Germany
引用
收藏
页码:477 / 478
页数:2
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