EFFECT OF SOLVENT ON PHOTOLYSIS OF ALPHA-LIPOIC ACID

被引：33

作者：

BROWN, PR

EDWARDS, JO

机构：

[1] Metcalf Laboratory, Brown University, Providence

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1969年 / 34卷 / 10期

关键词：

D O I：

10.1021/jo01262a072

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The photolysis of α-lipoic acid in different solvents was followed by tic and uv. It was found that a number of products are formed in each solution and the number and kind of product are dependent on the solvent. The chain length is determined by the kind of solvent; the length of the polymer chain decreased with increased availability of hydrogen atoms in the solvent. The amounts of products as well as the rate of formation of products are also solvent dependent. A mechanism is postulated in which the disulfide bond is broken homolytically in the first step. It is postulated that the reaction proceeds by chain transfer of hydrogen atoms from the solvent, causing short chains; by attack of the radicals on the other lipoic acid molecules, forming chains of longer length; or by the hydrolysis of the thio ketone formed by intramolecular abstraction of the tertiary hydrogen. © 1969, American Chemical Society. All rights reserved.

引用

页码：3131 / +

页数：1

共 14 条

[1] THE CHEMISTRY OF 1,2-DITHIOLANE (TRIMETHYLENE DISULFIDE) AS A MODEL FOR THE PRIMARY QUANTUM CONVERSION ACT IN PHOTOSYNTHESIS [J].