COLLAGEN GELS - DESIGN FOR A VITREOUS REPLACEMENT

被引：35
作者：
STENZEL, KH
DUNN, MW
RUBIN, AL
机构：
[1] Departments of Surgery (Ophthalmology), and Biochemistry, Rogosin Laboratories, New York Hospital-Cornell Medical Center, New York, NY
[2] Collagen Research Division, Japan Leather Company, Ltd., Tokyo
来源：
SCIENCE | 1969年 / 164卷 / 3885期
关键词：
D O I：
10.1126/science.164.3885.1282
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Clear, stable gels have been prepared from purified tropocollagen from calf skin; the collagen was solubilized with a proteolytic enzyme (Proctase) and stabilized by ultraviolet irradiation under nitrogen. These gels are clear, possess altered immunologic reactivity, and have properties of an ideal vitreous replacement. Implantations in rabbit and monkey eyes appear to be well tolerated, remain clear, and gradually disappear in about 2 months.
引用
收藏
页码：1282 / &
相关论文
共 8 条
1